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Genetic Screening in Manchester & Cheshire

At CLNQ in Cheshire & Manchester genetic screening is the analysis of your DNA or genes to identify if you have gene mutations that are associated with certain diseases or cancers.

These tests are performed using a sample of your saliva or blood. These screening tests are helpful if you are concerned about your risk of developing a specific disease or cancer.

After receiving a genetic screening Manchester & Cheshire patients can benefit whether the result is negative or positive. If the results are negative, there is some reassurance that you are not at a higher risk of developing the specific condition or cancer. Should the result be positive, you will be able to take action and seek advice to reduce risks, help your family learn about their risks and undergo further investigations if necessary to identify conditions earlier.

All of us have a 1 in 2 lifetime risk of cancer. There many different risks such as environment, lifestyle and hereditary factors. About 10-15% of most cancers are due to hereditary genetic mutations. If you can identify this risk it can allow development of plans to help detect and treat any conditions earlier. You can also share information with relatives so that they can learn if they are also at higher risk of specific cancers or conditions.

Cancer Screen

The cancer screen analyses 30 genes known to increase the risk of specific cancers. These cancers include:

  • Breast
  • Ovarian
  • Uterine
  • Colorectal
  • Melanoma
  • Stomach
  • Pancreatic
  • Prostate

Cardiac Screen (Heart)

This cardiac screening analyses 77 genes related to inherited heart conditions such as:

  • Arrhythmias
  • Cardiomyopathies
  • Thrombophilia
  • Aortopathies
  • Blood pressure
  • High Cholesterol

Genetic Screening Frequently Asked Questions

What happens if the genetic screening is positive?

If the results are positive then there is a mutation on the specific gene that increases your lifetime risk of developing that specific condition. This does not imply you have the condition or will definitely develop it but helps us become aware that your risks are higher than the general population.

What happens if the result is negative?

If your result is negative, this means that the gene mutation is not present that would be associated with an increased risk of the hereditary conditions being analysed. This does not eliminate your risk of developing the condition as there are other factors such as lifestyle and environmental factors. There may also be other mutations that may not be detected with the current technology or tests.

What is the process for genetic screening?

Our private GPs will take a medical history and family history that will identify your risk factors. They will identify which screening tests would be suitable for you. The test involves taking a sample of saliva (spit) or sometimes blood. This sample is then sent to a specialist laboratory for analysis. Your results will usually take between 4-6 weeks. When the results are available we will contact you to discuss them. If positive, a geneticist will contact you to discuss the implications of the results for the genetic screening in Manchester & Cheshire. The will discuss the outcomes and subsequent management if any is needed.

How much is genetic screening?

The cost will depend on the specific conditions that we are analysing. The price starts from £495.

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